Toray Filtryzer NF-H
Hemodialyzer
Features
The Filtryzer NF-H is the most advanced high flux PMMA membrane. It offers not only excellent biocompatibility and higher adsorption capacity of proteins like as previous models, but also improved the effect of anti coagulant.
Use
This device is the hollow fiber dialyzer which shall be used in acute or chronic hemo dialysis treatment in order that renal failure patients could remove the excessive water in the body and uremic toxins such as urea, creatinine, phosphate, β2-MG, etc.
Production sales agency：
Toray Industries, Inc.
Model number, specifications
Toray Filtryzer NF-H：
| Type | NF-1.3H | NF-1.6H | NF-1.8H | NF-2.1H | |
| Effective surface area (m2) | 1.3 | 1.6 | 1.8 | 2.1 | |
| UFR (Ultrafiltration coefficient) in vitro (mL/hr/mmHg) 1) | 36 | 43 | 48 | 55 | |
| Clearance in vitro (μm) 2) | |||||
| Urea（mL/min） | 186 | 190 | 192 | 193 | |
| Creatinine（mL/min） | 170 | 176 | 178 | 182 | |
| Phosphate（mL/min） | 161 | 168 | 172 | 176 | |
| Vitamin B12（mL/min） | 110 | 119 | 124 | 132 | |
| Inulin（mL/min） | 56 | 68 | 75 | 81 | |
| Housing material | Polystyrene | ||||
| Fibers | Meterial | Polymetylmethacrylate (PMMA) | |||
| Inner diameter (μm) | 200 | ||||
| Membrane thickness (μm) | 30 | ||||
| Sterilization | Gamma-ray Irradiation | ||||
| Maximum TMP (kPa(mmHg)) | 66 (500) | ||||
- Bovine blood, at a TMP of 50mmHg in accordance with ISO8637
- Aqueous solution, QB=200±4mL/min, QD=500±10mL/min, QF=10±2mL/min, Temp: 37±1℃
References
Review Articles：
Polymethylmethacrylate Membrane Dialyzer: Historic but Modern.
Torii Y et al., Blood Purif. 2022 Oct 20;52(Suppl 1):1-7.
Original Articles：
A new polymethylmetacrylate membrane improves the membrane adhesion of blood components and clinical efficacy.
Masakane I et al., Renal Replacement Therapy. 2017 3:32.
The clinical evaluation of novel polymethyl methacrylate membrane with a modified membrane surface: a multicenter pilot study.
Uchiumi N et al., Renal Replacement Therapy. 2018 4:32
Clinical advantages of a newly launched anti-thrombotic PMMA membrane for the nutritional status and dialysis-related symptoms in older chronic dialysis patients: a multicenter pilot study.
Masakane I et al., Replacement Therapy. 2021 7:31.
Examination of the Effect of Switching Dialysis Membranes on the Immune Response to Influenza Virus Vaccination in Hemodialysis Patients.
Tomo T et al., Blood Purif. 2023 Mar 30;52(Suppl 1):1-9.