Hemofilter
Features
HEMOFEEL™ CH is a hemofilter for continuous renal support made of polymethylmethacrylate (PMMA) membrane with excellent biocompatibility and also unique characteristics of absorbing proteins. In vitro experiments have shown that the PMMA hemofilter has an inflammatory cytokine adsorptive capability.
Use
HEMOFEEL™ CH is designed for the continuous replacement of the main activity of the kidneys by removing water and toxins at a slow and steady rate.
Production sales agency:
Toray Industries, Inc.
Model number, specifications
Type | CH-1.8W |
---|---|
Fibers | Polymethylmethacrylate (PMMA) |
Inside diameter (μm) | 240 |
Membrane thickness (μm) | 30 |
Effective surface area (m2) | 1.8 |
Sterilization | Gamma-ray Irradiation |
Blood volume *1 (mL) | 130 |
Sieving coefficient *2 | |
Albumin | 0.004 |
Inulin | 1.0 |
UFR in vitro *3 (mL/hr/mmHg) | 30 |
Max. TMP (kPa (mmHg)) | 66 (500) |
Range of blood flow rates (mL/min) | 100-300 |
References
Treatment of severe sepsis and septic shock by CHDF using a PMMA membrane hemofilter as a cytokine modulator
Nakamura M et al. Contrib Nephrol. 2010;166:73-82.
Continuous renal replacement therapy with a polymethyl methacrylate membrane hemofilter suppresses inflammation in patients after open-heart surgery with cardiopulmonary bypass
Mukaida H et al. J Artif Organs. 2018;21:188-195.
Continuous hemodiafiltration with PMMA Hemofilter in the treatment of patients with septic shock
Nakada TA et al. Mol Med. 2008;14:257-263.
Group A Streptococcal Toxic Shock-Like Syndrome in a Male Presenting as Primary Peritonitis: A Case Report and a Review in Japan
Sakuraba S et al. Case Rep Gastrointest Med. 2019:4984679.
The role of hypercytokinemia in the pathophysiology of tumor lysis syndrome (TLS) and the treatment with continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter (PMMA-CHDF)
Nakamura M et al. Transfus Apher Sci. 2009;40:41-47.
Comparison of interleukin-6 removal properties among hemofilters consisting of varying membrane materials and surface areas: an in vitro study
Hirayama Y et al. Blood Purif. 2011;31:18-25.