Toray Filtryzer NF-U
Hemodialyzer
Features
The Filtryzer NF-U is one of the advanced high flux PMMA membranes. It offers not only excellent biocompatibility and higher adsorption capacity of proteins like as previous models, but also improved the effect of anticoagulant. In addition, NF-U series has a feature of minimized albumin leakage, and it also allows to use comfortably for patients who are concerned about malnutrition.
Production sales agency：
Toray Industries, Inc.
Model number, specifications
Toray Filtryzer NF-U：
| Type | NF-1.3U | NF-1.6U | NF-1.8U | NF-2.1U | |
| Fibers | Effective surface area (m2) | 1.3 | 1.6 | 1.8 | 2.1 |
| Effectie length (mm) | 195 | ||||
| Inside diameter (μm) | 200 | ||||
| Membrane thickness (μm) | 30 | ||||
| Meterial | Polymetylmethacrylate (PMMA) | ||||
| Clearance (mL/min) * | Urea | 233 | 246 | 254 | 260 |
| Creatinine | 200 | 217 | 225 | 231 | |
| Phosphate | 182 | 198 | 208 | 217 | |
| Vitamin B12 | 110 | 128 | 140 | 149 | |
| Inulin | 62 | 72 | 77 | 85 | |
| UFR in vitro (mL/hr/mmHg) ** | 32 | 38 | 45 | 48 | |
| Housing material | Polystyrene | ||||
| Sterilization | Gamma-ray Irradiation | ||||
- * Clearance are typical data with aqueous solution. (QB: 300 mL, QD: 500±10 mL/min, QF: 10±2 mL/min, Temp.: 37±1 °C)
- ** UFRs are typical data with bovine blood. (Ht: 32±3 %, TP: 6.0±0.5 g/dL, QB: 300 mL/min, TMP: 50 mmHg, Temp.: 37±1 °C)
References
Review Articles：
Polymethylmethacrylate Membrane Dialyzer: Historic but Modern.
Torii Y et al., Blood Purif. 2022 Oct 20;52(Suppl 1):1-7.
Original Articles：
Evaluation and comparison of polysulfone TS-UL and PMMA NF-U dialyzers versus expanded hemodialysis and postdilution hemodiafiltration.
Maduell F et al., Artif Organs. 2021 45(9):E317-E323.
New polymethylmethacrylate membrane, NF-U, improves nutritional status and reduces patient-reported symptoms in older dialysis patients.
Chida T et al., Renal Replacement Therapy 2022 8:11.